BioMS Centre:

Country: Greece

City: Athens

Institution:

  • 2nd Department of Neurology, “Attikon” University Hospital, School of Medicine, National and Kapodistrian University of Athens

Website: http://attikonhospital.gov.gr

  • Tzartos NeuroDiagnosticss

Website: www.neurodiagnostics.gr



PI:  John Tzartos, Assoc. Prof of Neurology-Neuroimmunolgy, jtzartos@gmail.com (Attikon Hospital and Tzartos NeuroDiagnostics)

CoPI: Socrates Tzartos, Emeritus Prof of Immunobiology, stzartos@gmail.com (Tzartos NeuroDiagnostics)

Team members (name, position and contact e-mail):

Dimitrios Tzanetakos, Neurologist, Academic Fellow, tzanetakosdim@yahoo.com (Attikon Hospital)



Biomarker research interest of our group

We have special interest on biomarkers for NMOSD and related diseases, including autoantibodies to AQP4, MOG, GFAP and AQP1, and the proteins GFAP and IL6. We have discovered the presence of autoantibodies to aquaporin-1 (AQP1) in “seronegative” patients with clinico-imaging features of NMOSD, and have collected data suggesting that AQP1 antibodies may be pathogenic. In addition, based on our earlier findings, we are investigating the presence of EBV markers in lesions and various cell types of MS brains (including lymphocytes and neurons) aiming at understanding the possible role of EBV in MS induction.